Expression of CYB5D1 in cancer - Summary - The Human Protein Atlas

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CYB5D1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CYB5D1
Gene description	Cytochrome b5 domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA021632
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA021632

GENE INFORMATION
Gene name	CYB5D1 (HGNC Symbol)
Synonyms	FLJ32499
Description	Cytochrome b5 domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.1
Chromosome location (bp)	7857746 - 7862282
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000182224 (version 83.38)
Entrez gene	124637
UniProt	Q6P9G0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6P9G0
Antibodypedia	CYB5D1 antibodies

PROTEIN BROWSER

CYB5D1-001	CYB5D1-003	CYB5D1-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CYB5D1-001 ENSP00000331479 ENST00000332439	Q6P9G0 [Direct mapping] Cytochrome b5 domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0046872 [metal ion binding] Show all	228 aa 26.7 kDa	No	0
CYB5D1-003 ENSP00000459369 ENST00000571846	Q6P9G0 [Direct mapping] Cytochrome b5 domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0046872 [metal ion binding] Show all	157 aa 18.3 kDa	No	0
CYB5D1-005 ENSP00000461852 ENST00000570446	I3NI34 [Direct mapping] Cytochrome b5 domain-containing protein 1 Show all	Predicted intracellular proteins Show all		100 aa 11.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.