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KCNJ14

GENERAL INFORMATION

Gene name

 KCNJ14

Gene description

 Potassium channel, inwardly rectifying subfamily J, member 14

Protein class

 Predicted membrane proteins
Voltage-gated ion channels

Predicted localization

 Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Mixed
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 KCNJ14 (HGNC Symbol)

Synonyms

 IRK4, Kir2.4

Description

 Potassium channel, inwardly rectifying subfamily J, member 14 (HGNC Symbol)

Entrez gene summary

 Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel, and probably has a role in controlling the excitability of motor neurons. [provided by RefSeq, Feb 2013]

Chromosome

 19

Cytoband

 q13.33

Chromosome location (bp)

 48455509 - 48466980

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000182324 (version 83.38)

Entrez gene

 3770

UniProt

 Q9UNX9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UNX9

Antibodypedia

 KCNJ14 antibodies

PROTEIN BROWSER
KCNJ14-001
KCNJ14-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KCNJ14-001
ENSP00000375756
ENST00000391884
Q9UNX9 [Direct mapping]
ATP-sensitive inward rectifier potassium channel 14
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Voltage-gated ion channels
   Inwardly Rectifying Potassium Channels
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
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GO:0005242 [inward rectifier potassium channel activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006813 [potassium ion transport]
GO:0007268 [synaptic transmission]
GO:0008076 [voltage-gated potassium channel complex]
GO:0010107 [potassium ion import]
GO:0016021 [integral component of membrane]
GO:0030425 [dendrite]
GO:0034765 [regulation of ion transmembrane transport]
GO:0043025 [neuronal cell body]
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 436 aa
47.8 kDa 		No 3
KCNJ14-002
ENSP00000341479
ENST00000342291
Q9UNX9 [Direct mapping]
ATP-sensitive inward rectifier potassium channel 14
Show all
Voltage-gated ion channels
   Inwardly Rectifying Potassium Channels
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0005242 [inward rectifier potassium channel activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006813 [potassium ion transport]
GO:0007268 [synaptic transmission]
GO:0008076 [voltage-gated potassium channel complex]
GO:0010107 [potassium ion import]
GO:0016021 [integral component of membrane]
GO:0034765 [regulation of ion transmembrane transport]
Show all
 436 aa
47.8 kDa 		No 3

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.