Expression of MXRA7 in cancer - Summary - The Human Protein Atlas

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MXRA7

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MXRA7
Gene description	Matrix-remodelling associated 7
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (U-87 MG)
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Secreted protein, tissue location of RNA and protein might differ and correlation is complex. Caution, Splice and/or transcript discrepancy exists.
Reliability score	Uncertain based on 1 antibody. HPA044819
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PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (unfavourable) and liver cancer (unfavourable).
Urothelial cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044819

GENE INFORMATION
Gene name	MXRA7 (HGNC Symbol)
Synonyms	FLJ46603, PS1TP1, TMAP1
Description	Matrix-remodelling associated 7 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q25.1
Chromosome location (bp)	76672551 - 76711016
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000182534 (version 83.38)
Entrez gene	439921
UniProt	P84157 (UniProt - Evidence at protein level)
neXtProt	NX_P84157
Antibodypedia	MXRA7 antibodies

PROTEIN BROWSER

MXRA7-001	MXRA7-002	MXRA7-003	MXRA7-004	MXRA7-005	MXRA7-006	MXRA7-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MXRA7-001 ENSP00000391466 ENST00000449428	P84157 [Direct mapping] Matrix-remodeling-associated protein 7 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	170 aa 17.5 kDa	Yes	0
MXRA7-002 ENSP00000465103 ENST00000592148	Q6ZR64 [Direct mapping] HBV PreS1-transactivated protein 1; Matrix-remodeling-associated protein 7; cDNA FLJ46603 fis, clone THYMU3047513 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		213 aa 23.4 kDa	No	0
MXRA7-003 ENSP00000468020 ENST00000588114	K7EQX8 [Direct mapping] Matrix-remodeling-associated protein 7 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		15 aa 1.9 kDa	No	0
MXRA7-004 ENSP00000364176 ENST00000375036	P84157 [Direct mapping] Matrix-remodeling-associated protein 7 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	177 aa 18.2 kDa	Yes	0
MXRA7-005 ENSP00000467510 ENST00000589082	K7EPS4 [Direct mapping] Matrix-remodeling-associated protein 7 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		22 aa 2.6 kDa	No	0
MXRA7-006 ENSP00000466376 ENST00000585519	K7EQX8 [Direct mapping] Matrix-remodeling-associated protein 7 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		15 aa 1.9 kDa	No	0
MXRA7-007 ENSP00000348050 ENST00000355797	P84157 [Direct mapping] Matrix-remodeling-associated protein 7 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	204 aa 21.5 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.