Cell atlas - GALNT9 - The Human Protein Atlas

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GALNT9

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Vesicles

Human cell
	Vesicles

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GENERAL INFORMATION
Gene name	GALNT9
Gene description	Polypeptide N-acetylgalactosaminyltransferase 9
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to vesicles.
RNA cell category	Cell line enriched (U-87 MG)
Protein evidence	Evidence at transcript level
Main location	Localized to the Vesicles (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA075016
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (U-87 MG) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to vesicles.

Main location

Vesicles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA075016	A549	Vesicles
	HPA075016	SiHa	Vesicles
	HPA075016	U-2 OS	Vesicles

GENE INFORMATION
Gene name	GALNT9 (HGNC Symbol)
Synonyms	GALNAC-T9
Description	Polypeptide N-acetylgalactosaminyltransferase 9 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. This gene is expressed specifically in the brain, with highest expression in the cerebellum. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	12
Cytoband	q24.33
Chromosome location (bp)	132196372 - 132329349
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000182870 (version 83.38)
Entrez gene	50614
UniProt	Q9HCQ5 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9HCQ5
Antibodypedia	GALNT9 antibodies

PROTEIN BROWSER

GALNT9-001	GALNT9-002	GALNT9-004	GALNT9-005	GALNT9-006	GALNT9-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GALNT9-001 ENSP00000380488 ENST00000397325	Q9HCQ5 [Direct mapping] Polypeptide N-acetylgalactosaminyltransferase 9 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0004653 [polypeptide N-acetylgalactosaminyltransferase activity] GO:0006493 [protein O-linked glycosylation] GO:0016021 [integral component of membrane] GO:0016266 [O-glycan processing] GO:0030246 [carbohydrate binding] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0046872 [metal ion binding] Show all	237 aa 27.2 kDa	No	0
GALNT9-002 ENSP00000440544 ENST00000541995	Q9HCQ5 [Direct mapping] Polypeptide N-acetylgalactosaminyltransferase 9 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0004653 [polypeptide N-acetylgalactosaminyltransferase activity] GO:0006493 [protein O-linked glycosylation] GO:0016021 [integral component of membrane] GO:0016266 [O-glycan processing] GO:0030246 [carbohydrate binding] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0046872 [metal ion binding] Show all	237 aa 27.2 kDa	No	0
GALNT9-004 ENSP00000444709 ENST00000538356	F5H557 [Direct mapping] Polypeptide N-acetylgalactosaminyltransferase 9 Show all	Predicted intracellular proteins Show all		97 aa 11.7 kDa	No	0
GALNT9-005 ENSP00000438221 ENST00000542942	F5H317 [Direct mapping] Polypeptide N-acetylgalactosaminyltransferase 9 Show all	Predicted intracellular proteins Show all		54 aa 6.5 kDa	No	0
GALNT9-006 ENSP00000394446 ENST00000411988	H3BM10 [Direct mapping] Polypeptide N-acetylgalactosaminyltransferase 9 Show all	Predicted intracellular proteins Show all		376 aa 42.3 kDa	No	0
GALNT9-009 ENSP00000329846 ENST00000328957	J3KNN1 [Direct mapping] Polypeptide N-acetylgalactosaminyltransferase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0006486 [protein glycosylation] GO:0016021 [integral component of membrane] GO:0016757 [transferase activity, transferring glycosyl groups] GO:0030246 [carbohydrate binding] GO:0046872 [metal ion binding] Show all	603 aa 68.4 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.