Tissue expression of CYLC1 - Summary - The Human Protein Atlas

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CYLC1

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TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CYLC1
Gene description	Cylicin, basic protein of sperm head cytoskeleton 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in testis.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. HPA070355
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	CYLC1
Synonyms
Description	Cylicin, basic protein of sperm head cytoskeleton 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a sperm head cytoskeletal protein. The encoded protein is associated with the calyx of spermatozoa and spermatids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Chromosome	X
Cytoband	q21.1
Chromosome location (bp)	83861126 - 83886699
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183035 (version 83.38)
Entrez gene	1538
UniProt	P35663 (UniProt - Evidence at transcript level)
neXtProt	NX_P35663
Antibodypedia	CYLC1 antibodies

PROTEIN BROWSER

CYLC1-001	CYLC1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CYLC1-001 ENSP00000331556 ENST00000329312	P35663 [Direct mapping] Cylicin-1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005198 [structural molecule activity] GO:0005200 [structural constituent of cytoskeleton] GO:0005634 [nucleus] GO:0007275 [multicellular organismal development] GO:0007283 [spermatogenesis] GO:0030154 [cell differentiation] GO:0033150 [cytoskeletal calyx] GO:0043159 [acrosomal matrix] Show all	651 aa 74.2 kDa	No	0
CYLC1-201 ENSP00000480907 ENST00000621735	A0A087WXC8 [Direct mapping] Cylicin-1 Show all	Predicted intracellular proteins Show all	GO:0005200 [structural constituent of cytoskeleton] Show all	68 aa 7.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.