Cell atlas - AFMID - The Human Protein Atlas

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AFMID

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria

Human cell
	Mitochondria

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GENERAL INFORMATION
Gene name	AFMID
Gene description	Arylformamidase
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the mitochondria.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Mitochondria (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA023861
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the mitochondria.

Main location

Mitochondria (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA023861	Hep G2	Mitochondria
	HPA023861	PC-3	Mitochondria
	HPA023861	U-2 OS	Mitochondria

GENE INFORMATION
Gene name	AFMID (HGNC Symbol)
Synonyms	DKFZp686F03259, KF
Description	Arylformamidase (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q25.3
Chromosome location (bp)	78187317 - 78207701
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183077 (version 83.38)
Entrez gene	125061
UniProt	Q63HM1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q63HM1
Antibodypedia	AFMID antibodies

PROTEIN BROWSER

AFMID-001	AFMID-002	AFMID-004	AFMID-005	AFMID-006	AFMID-007	AFMID-009	AFMID-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AFMID-001 ENSP00000328938 ENST00000327898	Q63HM1 [Direct mapping] Kynurenine formamidase Show all	Enzymes ENZYME proteins Hydrolases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004061 [arylformamidase activity] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006569 [tryptophan catabolic process] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] GO:0019441 [tryptophan catabolic process to kynurenine] GO:0034354 ['de novo' NAD biosynthetic process from tryptophan] GO:0034641 [cellular nitrogen compound metabolic process] GO:0044281 [small molecule metabolic process] Show all	308 aa 34.5 kDa	No	0
AFMID-002 ENSP00000466859 ENST00000589256	W4VSQ7 [Direct mapping] Arylformamidase, isoform CRA_b; Kynurenine formamidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		57 aa 6.4 kDa	No	0
AFMID-004 ENSP00000464929 ENST00000588800	K7EIX3 [Direct mapping] Kynurenine formamidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		93 aa 10.7 kDa	No	0
AFMID-005 ENSP00000386890 ENST00000409257	Q63HM1 [Direct mapping] Kynurenine formamidase Show all	Enzymes ENZYME proteins Hydrolases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004061 [arylformamidase activity] GO:0005634 [nucleus] GO:0005829 [cytosol] GO:0006569 [tryptophan catabolic process] GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] GO:0019441 [tryptophan catabolic process to kynurenine] GO:0034354 ['de novo' NAD biosynthetic process from tryptophan] GO:0034641 [cellular nitrogen compound metabolic process] GO:0044281 [small molecule metabolic process] Show all	303 aa 34 kDa	No	0
AFMID-006 ENSP00000466515 ENST00000591256	K7EMI4 [Direct mapping] Kynurenine formamidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	206 aa 22.7 kDa	No	0
AFMID-007 ENSP00000466566 ENST00000586542	K7EMM5 [Direct mapping] Kynurenine formamidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		187 aa 20.6 kDa	No	0
AFMID-009 ENSP00000467365 ENST00000591952	K7EPF8 [Direct mapping] Kynurenine formamidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		84 aa 9.5 kDa	No	0
AFMID-015 ENSP00000466241 ENST00000586731	K7ELV9 [Direct mapping] Kynurenine formamidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		37 aa 4.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.