Expression of PRR36 in cancer - Summary - The Human Protein Atlas

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PRR36

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PRR36
Gene description	Proline rich 36
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (REH, SH-SY5Y)
HPA (normal tissue):	Tissue enriched (cerebral cortex)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA062741
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PROGNOSTIC SUMMARY
Prognostic marker in testis cancer (favourable).
Testis cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA062741

GENE INFORMATION
Gene name	PRR36
Synonyms
Description	Proline rich 36 (HGNC Symbol)
Entrez gene summary	This gene encodes a large protein of unknown function that contains internal regions of low complexity sequence. Alternative splicing results in multiple transcript variants. The transcript structure of the protein-coding variant at this locus is conserved between human and mouse. [provided by RefSeq, Oct 2013]
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	7868719 - 7874379
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183248 (version 83.38)
Entrez gene	80164
UniProt	Q9H6K5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H6K5
Antibodypedia	PRR36 antibodies

PROTEIN BROWSER

PRR36-001	PRR36-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRR36-001 ENSP00000485221 ENST00000615988	A0A096LNU1 [Direct mapping] Proline-rich protein 36 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		275 aa 28.2 kDa	No	0
PRR36-002 ENSP00000482374 ENST00000618550	Q9H6K5 [Direct mapping] Proline-rich protein 36 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		1346 aa 132.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.