Expression of FAM9A in cancer - Summary - The Human Protein Atlas

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FAM9A

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM9A
Gene description	Family with sequence similarity 9, member A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enriched (U-266/84)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA056076
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA056076

GENE INFORMATION
Gene name	FAM9A (HGNC Symbol)
Synonyms	TEX39A
Description	Family with sequence similarity 9, member A (HGNC Symbol)
Entrez gene summary	This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may be a nuclear protein that is localized to the nucleolus, and has some similarity to a synaptonemal complex protein. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011]
Chromosome	X
Cytoband	p22.31
Chromosome location (bp)	8790795 - 8801383
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183304 (version 83.38)
Entrez gene	171482
UniProt	Q8IZU1 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IZU1
Antibodypedia	FAM9A antibodies

PROTEIN BROWSER

FAM9A-001	FAM9A-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM9A-001 ENSP00000370391 ENST00000381003	Q8IZU1 [Direct mapping] Protein FAM9A Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0007286 [spermatid development] Show all	332 aa 37.3 kDa	No	0
FAM9A-201 ENSP00000440163 ENST00000543214	Q8IZU1 [Direct mapping] Protein FAM9A Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0007286 [spermatid development] Show all	332 aa 37.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.