Expression of CCDC159 in cancer - Summary - The Human Protein Atlas

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CCDC159

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CCDC159
Gene description	Coiled-coil domain containing 159
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA047126
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PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (favourable), pancreatic cancer (favourable), urothelial cancer (favourable) and ovarian cancer (favourable).
Endometrial cancer p<0.001 Pancreatic cancer p<0.001 Urothelial cancer p<0.001 Ovarian cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA047126

GENE INFORMATION
Gene name	CCDC159
Synonyms
Description	Coiled-coil domain containing 159 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	11344684 - 11354944
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183401 (version 83.38)
Entrez gene	126075
UniProt	P0C7I6 (UniProt - Evidence at transcript level)
neXtProt	NX_P0C7I6
Antibodypedia	CCDC159 antibodies

PROTEIN BROWSER

CCDC159-001	CCDC159-006	CCDC159-011	CCDC159-012	CCDC159-019	CCDC159-020	CCDC159-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC159-001 ENSP00000468232 ENST00000588790	P0C7I6 [Direct mapping] Coiled-coil domain-containing protein 159 Show all	Predicted intracellular proteins Show all		297 aa 33.7 kDa	No	0
CCDC159-006 ENSP00000465560 ENST00000586451	K7EKC7 [Direct mapping] Coiled-coil domain-containing protein 159 Show all	Predicted intracellular proteins Show all		140 aa 16.5 kDa	No	0
CCDC159-011 ENSP00000465790 ENST00000588592	K7EKU9 [Direct mapping] Coiled-coil domain-containing protein 159 Show all	Predicted intracellular proteins Show all		129 aa 15.1 kDa	No	0
CCDC159-012 ENSP00000466882 ENST00000587531	K7ENC2 [Direct mapping] Coiled-coil domain-containing protein 159 Show all	Predicted intracellular proteins Show all		110 aa 12.7 kDa	No	0
CCDC159-019 ENSP00000465218 ENST00000591691	K7EJK8 [Direct mapping] Coiled-coil domain-containing protein 159 Show all	Predicted intracellular proteins Show all		155 aa 16.8 kDa	No	0
CCDC159-020 ENSP00000466796 ENST00000591260	K7EN56 [Direct mapping] Coiled-coil domain-containing protein 159 Show all	Predicted intracellular proteins Show all		193 aa 21.5 kDa	No	0
CCDC159-201 ENSP00000402239 ENST00000458408	P0C7I6 [Direct mapping] Coiled-coil domain-containing protein 159 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all		297 aa 33.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.