Expression of PGPEP1L in cancer - Summary - The Human Protein Atlas

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PGPEP1L

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PGPEP1L
Gene description	Pyroglutamyl-peptidase I-like
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enhanced (U-2 OS)
HPA (normal tissue):	Group enriched (heart muscle, skeletal muscle, testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA041781
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA041781

GENE INFORMATION
Gene name	PGPEP1L
Synonyms
Description	Pyroglutamyl-peptidase I-like (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q26.3
Chromosome location (bp)	98968230 - 99007795
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000183571 (version 83.38)
Entrez gene	145814
UniProt	A6NFU8 (UniProt - Evidence at transcript level)
neXtProt	NX_A6NFU8
Antibodypedia	PGPEP1L antibodies

PROTEIN BROWSER

PGPEP1L-001	PGPEP1L-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PGPEP1L-001 ENSP00000368199 ENST00000378919	A6NFU8 [Direct mapping] Pyroglutamyl-peptidase 1-like protein Show all	Enzymes Peptidases Cysteine-type peptidases Predicted intracellular proteins Show all	GO:0006508 [proteolysis] GO:0008234 [cysteine-type peptidase activity] Show all	196 aa 21.6 kDa	No	0
PGPEP1L-002 ENSP00000437560 ENST00000535714	A6NFU8 [Direct mapping] Pyroglutamyl-peptidase 1-like protein Show all	Enzymes Peptidases Cysteine-type peptidases Predicted intracellular proteins Show all	GO:0006508 [proteolysis] GO:0008234 [cysteine-type peptidase activity] Show all	142 aa 15.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.