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FAM101B

GENERAL INFORMATION

Gene name

 FAM101B

Gene description

 Family with sequence similarity 101, member B

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Cell line enhanced (HMC-1)
HPA (normal tissue):Tissue enhanced (bone marrow)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA030879
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA030879

GENE INFORMATION

Gene name

 FAM101B (HGNC Symbol)

Synonyms

 MGC45871

Description

 Family with sequence similarity 101, member B (HGNC Symbol)

Entrez gene summary

Chromosome

 17

Cytoband

 p13.3

Chromosome location (bp)

 439978 - 445939

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000183688 (version 83.38)

Entrez gene

 359845

UniProt

 Q8N5W9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8N5W9

Antibodypedia

 FAM101B antibodies

PROTEIN BROWSER
FAM101B-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FAM101B-001
ENSP00000331915
ENST00000329099
Q8N5W9 [Direct mapping]
Filamin-interacting protein FAM101B
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0001837 [epithelial to mesenchymal transition]
GO:0005737 [cytoplasm]
GO:0015629 [actin cytoskeleton]
GO:0030036 [actin cytoskeleton organization]
GO:0031005 [filamin binding]
GO:0032432 [actin filament bundle]
GO:0048705 [skeletal system morphogenesis]
GO:0061182 [negative regulation of chondrocyte development]
GO:0061572 [actin filament bundle organization]
GO:1900158 [negative regulation of bone mineralization involved in bone maturation]
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 144 aa
16.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.