Cell atlas - TRAIP - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

TRAIP

TISSUE

premium

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Plasma membrane

Human cell
	Cytosol
	Plasma Membrane

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	TRAIP
Gene description	TRAF interacting protein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the plasma membrane & cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (supported), Cytosol (approved)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA036261
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the plasma membrane & cytosol.

Main location

Plasma membrane (supported), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA036261	A-431	Plasma membrane
	HPA036261	A-431	Cytosol
	HPA036261	U-2 OS	Plasma membrane
	HPA036261	U-2 OS	Cytosol
	HPA036261	U-251 MG	Plasma membrane
	HPA036261	U-251 MG	Cytosol

GENE INFORMATION
Gene name	TRAIP (HGNC Symbol)
Synonyms	RNF206, TRIP
Description	TRAF interacting protein (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008]
Chromosome	3
Cytoband	p21.31
Chromosome location (bp)	49828599 - 49856574
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000183763 (version 83.38)
Entrez gene	10293
UniProt	Q9BWF2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BWF2
Antibodypedia	TRAIP antibodies

PROTEIN BROWSER

TRAIP-001	TRAIP-005	TRAIP-007	TRAIP-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRAIP-001 ENSP00000328203 ENST00000331456	Q9BWF2 [Direct mapping] E3 ubiquitin-protein ligase TRAIP Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004842 [ubiquitin-protein transferase activity] GO:0005057 [receptor signaling protein activity] GO:0005515 [protein binding] GO:0005730 [nucleolus] GO:0006915 [apoptotic process] GO:0007165 [signal transduction] GO:0008270 [zinc ion binding] GO:0008283 [cell proliferation] GO:0010804 [negative regulation of tumor necrosis factor-mediated signaling pathway] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0032688 [negative regulation of interferon-beta production] GO:0035556 [intracellular signal transduction] GO:0048471 [perinuclear region of cytoplasm] GO:0061630 [ubiquitin protein ligase activity] Show all	469 aa 53.3 kDa	No	0
TRAIP-005 ENSP00000420085 ENST00000469027	E7ETV1 [Direct mapping] E3 ubiquitin-protein ligase TRAIP Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] Show all	284 aa 31.8 kDa	No	0
TRAIP-007 ENSP00000418544 ENST00000482582	E7EN91 [Direct mapping] E3 ubiquitin-protein ligase TRAIP Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] Show all	266 aa 30.7 kDa	No	0
TRAIP-009 ENSP00000419350 ENST00000482243	E7EW89 [Direct mapping] E3 ubiquitin-protein ligase TRAIP Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] Show all	155 aa 18 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.