Expression of SDR42E2 in cancer - Summary - The Human Protein Atlas

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SDR42E2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SDR42E2
Gene description	Short chain dehydrogenase/reductase family 42E, member 2
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enriched (RPMI-8226)
HPA (normal tissue):	Tissue enhanced (fallopian tube, testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results.
Reliability score	Uncertain based on 1 antibody. HPA061278
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA061278

GENE INFORMATION
Gene name	SDR42E2
Synonyms
Description	Short chain dehydrogenase/reductase family 42E, member 2 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p12.2
Chromosome location (bp)	22165583 - 22191754
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000183921 (version 83.38)
Entrez gene
UniProt	A6NKP2 (UniProt - Inferred from homology)
neXtProt	NX_A6NKP2
Antibodypedia	SDR42E2 antibodies

PROTEIN BROWSER

SDR42E2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SDR42E2-001 ENSP00000473474 ENST00000602312	A6NKP2 [Direct mapping] Putative short-chain dehydrogenase/reductase family 42E member 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003854 [3-beta-hydroxy-delta5-steroid dehydrogenase activity] GO:0006694 [steroid biosynthetic process] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0055114 [oxidation-reduction process] Show all	422 aa 46.9 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.