Fields »
ABOUT
HELP
BLOG
FAM132A

GENERAL INFORMATION

Gene name

 FAM132A

Gene description

 Family with sequence similarity 132, member A

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Group enriched (EFO-21, U-2 OS)
HPA (normal tissue):Tissue enhanced (duodenum, small intestine)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic and membranous expression in several tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Reliability score

 Approved based on 1 antibody.
HPA024107
SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA024107

GENE INFORMATION

Gene name

 FAM132A (HGNC Symbol)

Synonyms

 C1QDC2, C1QTNF12, CTRP12, MGC105127

Description

 Family with sequence similarity 132, member A (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 p36.33

Chromosome location (bp)

 1242446 - 1246722

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000184163 (version 83.38)

Entrez gene

 388581

UniProt

 Q5T7M4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5T7M4

Antibodypedia

 FAM132A antibodies

PROTEIN BROWSER
FAM132A-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FAM132A-001
ENSP00000329137
ENST00000330388
Q5T7M4 [Direct mapping]
Adipolin Adipolin fCTRP12 Adipolin gCTRP12
Show all
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0005179 [hormone activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0010906 [regulation of glucose metabolic process]
GO:0035774 [positive regulation of insulin secretion involved in cellular response to glucose stimulus]
GO:0045721 [negative regulation of gluconeogenesis]
GO:0046324 [regulation of glucose import]
GO:0046326 [positive regulation of glucose import]
GO:0046628 [positive regulation of insulin receptor signaling pathway]
GO:0050728 [negative regulation of inflammatory response]
GO:0051897 [positive regulation of protein kinase B signaling]
Show all
 302 aa
32.4 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.