Expression of SRPK3 in cancer - Summary - The Human Protein Atlas

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SRPK3

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	SRPK3
Gene description	SRSF protein kinase 3
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (RH-30)
HPA (normal tissue):	Group enriched (heart muscle, skeletal muscle)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	SRPK3 (HGNC Symbol)
Synonyms	MSSK1, STK23
Description	SRSF protein kinase 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Chromosome	X
Cytoband	q28
Chromosome location (bp)	153776412 - 153785732
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184343 (version 83.38)
Entrez gene	26576
UniProt	Q9UPE1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UPE1
Antibodypedia	SRPK3 antibodies

PROTEIN BROWSER

SRPK3-001	SRPK3-002	SRPK3-003	SRPK3-004	SRPK3-005	SRPK3-006	SRPK3-007	SRPK3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SRPK3-001 ENSP00000359126 ENST00000370108	A8MPY5 [Direct mapping] SRSF protein kinase 3; Serine/threonine kinase 23, isoform CRA_a Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	534 aa 59.1 kDa	No	0
SRPK3-002 ENSP00000359118 ENST00000370100	A8MPP7 [Direct mapping] SRSF protein kinase 3 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	492 aa 55.4 kDa	No	0
SRPK3-003 ENSP00000402300 ENST00000430541	H7C1T4 [Direct mapping] SRSF protein kinase 3 Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	205 aa 22.3 kDa	No	0
SRPK3-004 ENSP00000406166 ENST00000458681	H7C2I2 [Direct mapping] SRSF protein kinase 3 Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	129 aa 14.7 kDa	No	0
SRPK3-005 ENSP00000359122 ENST00000370104	Q9UPE1 [Direct mapping] SRSF protein kinase 3 Show all	Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005575 [cellular_component] GO:0006468 [protein phosphorylation] GO:0030154 [cell differentiation] GO:0060537 [muscle tissue development] Show all	566 aa 61.9 kDa	No	0
SRPK3-006 ENSP00000359119 ENST00000370101	Q9UPE1 [Direct mapping] SRSF protein kinase 3 Show all	Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005575 [cellular_component] GO:0006468 [protein phosphorylation] GO:0007519 [skeletal muscle tissue development] GO:0030154 [cell differentiation] GO:0060537 [muscle tissue development] Show all	567 aa 62 kDa	No	0
SRPK3-007 ENSP00000420058 ENST00000489426	E7ETV6 [Direct mapping] SRSF protein kinase 3 Show all	THUMBUP predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	634 aa 69.2 kDa	No	0
SRPK3-201 ENSP00000377376 ENST00000393786	Q9UPE1 [Direct mapping] SRSF protein kinase 3 Show all	Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005575 [cellular_component] GO:0006468 [protein phosphorylation] GO:0030154 [cell differentiation] GO:0060537 [muscle tissue development] Show all	533 aa 59 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.