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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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PABPC1L2B
  • TISSUE

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PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

PABPC1L2B

Gene description

Poly(A) binding protein, cytoplasmic 1-like 2B

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Tissue enriched (prostate cancer)
HPA (cell line):Cell line enhanced (NTERA-2)
HPA (normal tissue):Group enriched (cerebral cortex, prostate)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Expression in processes of cerebral cortex and hypothalamus.

ANTIBODY IHC RELIABILITY

Data reliability
description

Pending external verification. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.

Reliability score

Approved based on 1 antibody.
HPA041573
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PROGNOSTIC SUMMARY

Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Tissue enriched (prostate cancer)

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA041573

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Cancer tissue were negative.

GENE INFORMATION

Gene name

PABPC1L2B (HGNC Symbol)

Synonyms

RBM32B

Description

Poly(A) binding protein, cytoplasmic 1-like 2B (HGNC Symbol)

Entrez gene summary

Chromosome

X

Cytoband

q13.2

Chromosome location (bp)

73003517 - 73005713

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000184388 (version 83.38)

Entrez gene

645974

UniProt

Q5JQF8 (UniProt - Evidence at transcript level)

neXtProt

NX_Q5JQF8

Antibodypedia

PABPC1L2B antibodies

PROTEIN BROWSER

PABPC1L2B-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PABPC1L2B-001
ENSP00000362621
ENST00000373521
Q5JQF8 [Direct mapping]
Polyadenylate-binding protein 1-like 2
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Predicted intracellular proteins
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GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0070062 [extracellular exosome]
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200 aa
22.8 kDa
No 0

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