Expression of PABPC1L2B in cancer - Summary - The Human Protein Atlas

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PABPC1L2B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PABPC1L2B
Gene description	Poly(A) binding protein, cytoplasmic 1-like 2B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (prostate cancer)
HPA (cell line):	Cell line enhanced (NTERA-2)
HPA (normal tissue):	Group enriched (cerebral cortex, prostate)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Expression in processes of cerebral cortex and hypothalamus.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 1 antibody. HPA041573
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (prostate cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA041573

Cancer	Cancer staining	Protein expression of normal tissue
Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma

Cancer	Cancer staining	Protein expression of normal tissue
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary	Cancer tissue were negative.

GENE INFORMATION
Gene name	PABPC1L2B (HGNC Symbol)
Synonyms	RBM32B
Description	Poly(A) binding protein, cytoplasmic 1-like 2B (HGNC Symbol)
Entrez gene summary
Chromosome	X
Cytoband	q13.2
Chromosome location (bp)	73003517 - 73005713
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000184388 (version 83.38)
Entrez gene	645974
UniProt	Q5JQF8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5JQF8
Antibodypedia	PABPC1L2B antibodies

PROTEIN BROWSER

PABPC1L2B-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PABPC1L2B-001 ENSP00000362621 ENST00000373521	Q5JQF8 [Direct mapping] Polyadenylate-binding protein 1-like 2 Show all	Predicted intracellular proteins Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0070062 [extracellular exosome] Show all	200 aa 22.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.