Fields »
ABOUT
HELP
BLOG
BPIFC

GENERAL INFORMATION

Gene name

 BPIFC

Gene description

 BPI fold containing family C

Protein class

 Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Group enriched (head and neck cancer, melanoma)
HPA (cell line):Cell line enhanced (SCLC-21H)
HPA (normal tissue):Tissue enriched (skin)

Protein evidence

 Evidence at transcript level

Protein expression
normal tissue

 Cytoplasmic expression in epidermal cells.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

 Uncertain based on 2 antibodies.
HPA037665 , HPA043306
SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Group enriched (head and neck cancer, melanoma)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA037665
HPA043306

GENE INFORMATION

Gene name

 BPIFC (HGNC Symbol)

Synonyms

 BPIL2, dJ149A16.7

Description

 BPI fold containing family C (HGNC Symbol)

Entrez gene summary

Chromosome

 22

Cytoband

 q12.3

Chromosome location (bp)

 32413847 - 32464484

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000184459 (version 83.38)

Entrez gene

 254240

UniProt

 Q8NFQ6 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8NFQ6

Antibodypedia

 BPIFC antibodies

PROTEIN BROWSER
BPIFC-010
BPIFC-011
BPIFC-201
BPIFC-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
BPIFC-010
ENSP00000380594
ENST00000397452
Q8NFQ6 [Direct mapping]
BPI fold-containing family C protein
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0001530 [lipopolysaccharide binding]
GO:0005543 [phospholipid binding]
GO:0005615 [extracellular space]
GO:0008289 [lipid binding]
Show all
 507 aa
56.5 kDa 		Yes 0
BPIFC-011
ENSP00000380592
ENST00000397450
Q5TI88 [Direct mapping]
BPI fold-containing family C protein
Show all
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0008289 [lipid binding]
Show all
 82 aa
9.4 kDa 		Yes 0
BPIFC-201
ENSP00000300399
ENST00000300399
Q8NFQ6 [Direct mapping]
BPI fold-containing family C protein
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0001530 [lipopolysaccharide binding]
GO:0005543 [phospholipid binding]
GO:0005615 [extracellular space]
GO:0008289 [lipid binding]
Show all
 507 aa
56.5 kDa 		Yes 0
BPIFC-202
ENSP00000439123
ENST00000534972
Q8NFQ6 [Direct mapping]
BPI fold-containing family C protein
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0001530 [lipopolysaccharide binding]
GO:0005543 [phospholipid binding]
GO:0005615 [extracellular space]
GO:0008289 [lipid binding]
Show all
 264 aa
29.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.