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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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ZFP1
  • TISSUE

  • CELL

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PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

ZFP1

Gene description

ZFP1 zinc finger protein

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

6
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

Uncertain based on 1 antibody.
HPA062910
SHOW MORE

PROGNOSTIC SUMMARY

Prognostic marker in glioma (favourable) and stomach cancer (unfavourable).
Glioma p<0.001
Stomach cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Urothelial cancer

STAINING SUMMARY

HPA062910

Cancer

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Cancer

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

A subset of cancer cells in a few cases of lymphoma showed moderate cytoplasmic staining. Cases of melanoma, urothelial and ovarian cancer displayed weak to moderate cytoplasmic and nuclear positivity. A single case of stomach cancer showed strong immunoreactivity. Remaining cancer tissues were negative.

GENE INFORMATION

Gene name

ZFP1 (HGNC Symbol)

Synonyms

FLJ34243, ZNF475

Description

ZFP1 zinc finger protein (HGNC Symbol)

Entrez gene summary

Chromosome

16

Cytoband

q23.1

Chromosome location (bp)

75148492 - 75172236

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000184517 (version 83.38)

Entrez gene

162239

UniProt

Q6P2D0 (UniProt - Evidence at protein level)

neXtProt

NX_Q6P2D0

Antibodypedia

ZFP1 antibodies

PROTEIN BROWSER

ZFP1-001
ZFP1-002
ZFP1-005
ZFP1-006
ZFP1-007
ZFP1-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ZFP1-001
ENSP00000377080
ENST00000393430
Q6P2D0 [Direct mapping]
Zinc finger protein 1 homolog
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
Show all
407 aa
47.5 kDa
No 0
ZFP1-002
ENSP00000457941
ENST00000464850
H3BV40 [Direct mapping]
Zinc finger protein 1 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
76 aa
8.9 kDa
No 0
ZFP1-005
ENSP00000455627
ENST00000567481
H3BV40 [Direct mapping]
Zinc finger protein 1 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
76 aa
8.9 kDa
No 0
ZFP1-006
ENSP00000457044
ENST00000570010
Q6P2D0 [Direct mapping]
Zinc finger protein 1 homolog
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
Show all
407 aa
47.5 kDa
No 0
ZFP1-007
ENSP00000454286
ENST00000568079
H3BM94 [Direct mapping]
Zinc finger protein 1 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
28 aa
3.4 kDa
No 0
ZFP1-008
ENSP00000333192
ENST00000332307
J3KNQ1 [Direct mapping]
Zinc finger protein 1 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
Show all
374 aa
43.7 kDa
No 0

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