Tissue expression of XPOT - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	XPOT
Gene description	Exportin, tRNA
Protein class	Predicted intracellular proteins Transporters
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	XPOT (HGNC Symbol)
Synonyms	XPO3
Description	Exportin, tRNA (HGNC Symbol)
Entrez gene summary	This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN. [provided by RefSeq, Jul 2008]
Chromosome	12
Cytoband	q14.2
Chromosome location (bp)	64404350 - 64451127
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184575 (version 83.38)
Entrez gene	11260
UniProt	O43592 (UniProt - Evidence at protein level)
neXtProt	NX_O43592
Antibodypedia	XPOT antibodies

PROTEIN BROWSER

XPOT-001	XPOT-003	XPOT-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
XPOT-001 ENSP00000327821 ENST00000332707	O43592 [Direct mapping] Exportin-T Show all	Transporters Transporter channels and pores MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000049 [tRNA binding] GO:0005488 [binding] GO:0005643 [nuclear pore] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006409 [tRNA export from nucleus] GO:0006886 [intracellular protein transport] GO:0008033 [tRNA processing] GO:0008536 [Ran GTPase binding] GO:0010467 [gene expression] GO:0015932 [nucleobase-containing compound transmembrane transporter activity] GO:0016363 [nuclear matrix] GO:0071528 [tRNA re-export from nucleus] Show all	962 aa 110 kDa	No	0
XPOT-003 ENSP00000441376 ENST00000540203	F5GYW6 [Direct mapping] Exportin-T Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] Show all	60 aa 6.9 kDa	No	0
XPOT-004 ENSP00000383722 ENST00000400935	F8WDU6 [Direct mapping] Exportin-T Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006886 [intracellular protein transport] GO:0008536 [Ran GTPase binding] Show all	202 aa 23.8 kDa	No	0