Expression of PRR16 in cancer - Summary - The Human Protein Atlas

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PRR16

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PRR16
Gene description	Proline rich 16
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (prostate cancer)
HPA (cell line):	Cell line enhanced (ASC TERT1, BJ hTERT+, LHCN-M2, U-138 MG)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA049254
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (prostate cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA049254

GENE INFORMATION
Gene name	PRR16 (HGNC Symbol)
Synonyms	DSC54
Description	Proline rich 16 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q23.1
Chromosome location (bp)	120464278 - 120687332
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184838 (version 83.38)
Entrez gene	51334
UniProt	Q569H4 (UniProt - Evidence at protein level)
neXtProt	NX_Q569H4
Antibodypedia	PRR16 antibodies

PROTEIN BROWSER

PRR16-001	PRR16-002	PRR16-003	PRR16-004	PRR16-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRR16-001 ENSP00000368869 ENST00000379551	Q569H4 [Direct mapping] Protein Largen Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0045727 [positive regulation of translation] GO:0045793 [positive regulation of cell size] Show all	281 aa 30.4 kDa	No	0
PRR16-002 ENSP00000385118 ENST00000407149	Q569H4 [Direct mapping] Protein Largen Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0045727 [positive regulation of translation] GO:0045793 [positive regulation of cell size] Show all	304 aa 32.8 kDa	No	0
PRR16-003 ENSP00000423446 ENST00000505123	Q569H4 [Direct mapping] Protein Largen Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0045727 [positive regulation of translation] GO:0045793 [positive regulation of cell size] Show all	234 aa 25.3 kDa	No	0
PRR16-004 ENSP00000421256 ENST00000509923	D6RGF0 [Direct mapping] Protein Largen Show all	Predicted intracellular proteins Show all		142 aa 15.2 kDa	No	0
PRR16-201 ENSP00000405491 ENST00000446965	A0A0A0MSW7 [Direct mapping] Protein Largen Show all	Predicted intracellular proteins Show all		251 aa 27.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.