Expression of RBM33 in cancer - Summary - The Human Protein Atlas

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RBM33

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RBM33
Gene description	RNA binding motif protein 33
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General nuclear and cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 3 antibodies. HPA019232 , HPA021497 , HPA021768
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PROGNOSTIC SUMMARY
Prognostic marker in head and neck cancer (favourable), renal cancer (unfavourable) and urothelial cancer (favourable).
Head and neck cancer p<0.001 Renal cancer p<0.001 Urothelial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA019232	HPA021497	HPA021768

GENE INFORMATION
Gene name	RBM33 (HGNC Symbol)
Synonyms	DKFZp434D1319, DKFZp686F102, MGC20460, PRR8
Description	RNA binding motif protein 33 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q36.3
Chromosome location (bp)	155644451 - 155781485
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184863 (version 83.38)
Entrez gene	155435
UniProt	Q96EV2 (UniProt - Evidence at protein level)
neXtProt	NX_Q96EV2
Antibodypedia	RBM33 antibodies

PROTEIN BROWSER

RBM33-001	RBM33-002	RBM33-003	RBM33-004	RBM33-005	RBM33-007	RBM33-008	RBM33-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RBM33-001 ENSP00000341583 ENST00000341148	A0A0C4DFS3 [Direct mapping] RNA-binding protein 33 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] Show all	106 aa 11.7 kDa	No	0
RBM33-002 ENSP00000405793 ENST00000438356	C9J7M3 [Direct mapping] RNA-binding protein 33 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		28 aa 3.1 kDa	No	0
RBM33-003 ENSP00000376514 ENST00000392761	H0Y3K4 [Direct mapping] RNA-binding protein 33 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		909 aa 100.2 kDa	No	0
RBM33-004 ENSP00000376510 ENST00000392755	H0Y3K3 [Direct mapping] RNA-binding protein 33 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] Show all	84 aa 8.8 kDa	No	0
RBM33-005 ENSP00000376513 ENST00000392759	A8MTF7 [Direct mapping] RNA-binding protein 33 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		308 aa 34.7 kDa	No	0
RBM33-007 ENSP00000384160 ENST00000401878	Q96EV2 [Direct mapping] RNA-binding protein 33 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0044822 [poly(A) RNA binding] Show all	1170 aa 130 kDa	No	0
RBM33-008 ENSP00000287912 ENST00000287912	Q96EV2 [Direct mapping] RNA-binding protein 33 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0044822 [poly(A) RNA binding] Show all	268 aa 30.2 kDa	No	0
RBM33-010 ENSP00000394987 ENST00000440108	H7C0H2 [Direct mapping] RNA-binding protein 33 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		342 aa 39 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.