Expression of BTBD6 in cancer - Summary - The Human Protein Atlas

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BTBD6

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	BTBD6
Gene description	BTB (POZ) domain containing 6
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues, including lens.

ANTIBODY IHC RELIABILITY
Data reliability description	External characterization data supports antibody staining in lens.
Reliability score	Approved based on 1 antibody. HPA031355
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable), breast cancer (favourable) and pancreatic cancer (favourable).
Renal cancer p<0.001 Breast cancer p<0.001 Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA031355

GENE INFORMATION
Gene name	BTBD6 (HGNC Symbol)
Synonyms	BDPL
Description	BTB (POZ) domain containing 6 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q32.33
Chromosome location (bp)	105248490 - 105251093
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184887 (version 83.38)
Entrez gene	90135
UniProt	Q96KE9 (UniProt - Evidence at protein level)
neXtProt	NX_Q96KE9
Antibodypedia	BTBD6 antibodies

PROTEIN BROWSER

BTBD6-001	BTBD6-003	BTBD6-005	BTBD6-201	BTBD6-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BTBD6-001 ENSP00000376337 ENST00000392554	Q96KE9 [Direct mapping] BTB/POZ domain-containing protein 6 Show all	Predicted intracellular proteins Show all	GO:0000932 [cytoplasmic mRNA processing body] GO:0005515 [protein binding] Show all	485 aa 53.4 kDa	No	0
BTBD6-003 ENSP00000418150 ENST00000463376	Q96KE9 [Direct mapping] BTB/POZ domain-containing protein 6 Show all	Predicted intracellular proteins Show all	GO:0000932 [cytoplasmic mRNA processing body] GO:0005515 [protein binding] Show all	410 aa 45.9 kDa	No	0
BTBD6-005 ENSP00000446223 ENST00000537513	F8VPC8 [Direct mapping] BTB/POZ domain-containing protein 6 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	407 aa 45 kDa	No	0
BTBD6-201 ENSP00000329361 ENST00000327471	Q96KE9 [Direct mapping] BTB/POZ domain-containing protein 6 Show all	Predicted intracellular proteins Show all	GO:0000932 [cytoplasmic mRNA processing body] GO:0005515 [protein binding] Show all	410 aa 45.9 kDa	No	0
BTBD6-202 ENSP00000443091 ENST00000536364	Q96KE9 [Direct mapping] BTB/POZ domain-containing protein 6 Show all	Predicted intracellular proteins Show all	GO:0000932 [cytoplasmic mRNA processing body] GO:0005515 [protein binding] Show all	485 aa 53.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.