Cell atlas - NOC4L - The Human Protein Atlas

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NOC4L

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoli
	Nucleus

Human cell
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	NOC4L
Gene description	Nucleolar complex associated 4 homolog
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoli. In addition localized to the nucleus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli (supported)
Additional location	In addition localized to the Nucleus (supported)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA053424
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoli. In addition localized to the nucleus.

Main location

Nucleoli (supported)

Additional location

Nucleus (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA053424	A-431	Nucleoli	Intensity
	HPA053424	U-2 OS	Nucleoli
	HPA053424	U-251 MG	Nucleus
	HPA053424	U-251 MG	Nucleoli

GENE INFORMATION
Gene name	NOC4L (HGNC Symbol)
Synonyms	MGC3162, NET49, UTP19
Description	Nucleolar complex associated 4 homolog (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q24.33
Chromosome location (bp)	132144448 - 132152473
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000184967 (version 83.38)
Entrez gene	79050
UniProt	Q9BVI4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BVI4
Antibodypedia	NOC4L antibodies

PROTEIN BROWSER

NOC4L-001	NOC4L-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NOC4L-001 ENSP00000328854 ENST00000330579	Q9BVI4 [Direct mapping] Nucleolar complex protein 4 homolog Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0006364 [rRNA processing] GO:0016021 [integral component of membrane] GO:0030692 [Noc4p-Nop14p complex] GO:0031965 [nuclear membrane] GO:0032040 [small-subunit processome] GO:0044822 [poly(A) RNA binding] Show all	516 aa 58.5 kDa	No	0
NOC4L-002 ENSP00000438255 ENST00000541954	F5H303 [Direct mapping] Nucleolar complex protein 4 homolog Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0030692 [Noc4p-Nop14p complex] GO:0032040 [small-subunit processome] GO:0042254 [ribosome biogenesis] Show all	270 aa 31.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.