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NDUFA6

GENERAL INFORMATION

Gene name

 NDUFA6

Gene description

 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable), cervical cancer (favourable) and endometrial cancer (favourable).
Renal cancer p<0.001
Cervical cancer p<0.001
Endometrial cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 NDUFA6 (HGNC Symbol)

Synonyms

 B14, CI-B14, LYRM6, NADHB14

Description

 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa (HGNC Symbol)

Entrez gene summary

Chromosome

 22

Cytoband

 q13.2

Chromosome location (bp)

 42085525 - 42090955

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000184983 (version 83.38)

Entrez gene

 4700

UniProt

 P56556 (UniProt - Evidence at protein level)

neXtProt

 NX_P56556

Antibodypedia

 NDUFA6 antibodies

PROTEIN BROWSER
NDUFA6-001
NDUFA6-002
NDUFA6-003
NDUFA6-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NDUFA6-001
ENSP00000418842
ENST00000498737
P56556 [Direct mapping]
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0005747 [mitochondrial respiratory chain complex I]
GO:0006120 [mitochondrial electron transport, NADH to ubiquinone]
GO:0006979 [response to oxidative stress]
GO:0008137 [NADH dehydrogenase (ubiquinone) activity]
GO:0022904 [respiratory electron transport chain]
GO:0031966 [mitochondrial membrane]
GO:0044237 [cellular metabolic process]
GO:0044281 [small molecule metabolic process]
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 154 aa
17.9 kDa 		No 0
NDUFA6-002
ENSP00000473478
ENST00000470753
R4GN43 [Direct mapping]
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 71 aa
8.5 kDa 		No 0
NDUFA6-003
ENSP00000473461
ENST00000602404
A0A0C4DGS0 [Direct mapping]
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005743 [mitochondrial inner membrane]
GO:0055114 [oxidation-reduction process]
GO:0070469 [respiratory chain]
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 128 aa
15.1 kDa 		No 0
NDUFA6-201
ENSP00000482543
ENST00000617763
P56556 [Direct mapping]
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005743 [mitochondrial inner membrane]
GO:0005747 [mitochondrial respiratory chain complex I]
GO:0006120 [mitochondrial electron transport, NADH to ubiquinone]
GO:0006979 [response to oxidative stress]
GO:0008137 [NADH dehydrogenase (ubiquinone) activity]
GO:0022904 [respiratory electron transport chain]
GO:0031966 [mitochondrial membrane]
GO:0044237 [cellular metabolic process]
GO:0044281 [small molecule metabolic process]
Show all
 154 aa
17.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.