Tissue expression of NT5C1B - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	NT5C1B
Gene description	5'-nucleotidase, cytosolic IB
Protein class	Enzymes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at transcript level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 1 antibody. HPA056683
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	NT5C1B (HGNC Symbol)
Synonyms	AIRP, CN-IB
Description	5'-nucleotidase, cytosolic IB (HGNC Symbol)
Entrez gene summary	Cytosolic 5-prime nucleotidases, such as NT5C1B, catalyze production of adenosine, which regulates diverse physiologic processes (Sala-Newby and Newby, 2001 [PubMed 11690631]).[supplied by OMIM, Mar 2008]
Chromosome	2
Cytoband	p24.2
Chromosome location (bp)	18562872 - 18589572
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000185013 (version 83.38)
Entrez gene	93034
UniProt	Q96P26 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96P26
Antibodypedia	NT5C1B antibodies

PROTEIN BROWSER

NT5C1B-001	NT5C1B-002	NT5C1B-006	NT5C1B-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NT5C1B-001 ENSP00000305979 ENST00000304081	Q96P26 [Direct mapping] Cytosolic 5'-nucleotidase 1B Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006144 [purine nucleobase metabolic process] GO:0006195 [purine nucleotide catabolic process] GO:0008253 [5'-nucleotidase activity] GO:0009117 [nucleotide metabolic process] GO:0016311 [dephosphorylation] GO:0044281 [small molecule metabolic process] GO:0055086 [nucleobase-containing small molecule metabolic process] Show all	550 aa 61.9 kDa	No	0
NT5C1B-002 ENSP00000352904 ENST00000359846	Q96P26 [Direct mapping] Cytosolic 5'-nucleotidase 1B Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006144 [purine nucleobase metabolic process] GO:0006195 [purine nucleotide catabolic process] GO:0008253 [5'-nucleotidase activity] GO:0009117 [nucleotide metabolic process] GO:0016311 [dephosphorylation] GO:0044281 [small molecule metabolic process] GO:0055086 [nucleobase-containing small molecule metabolic process] Show all	610 aa 68.8 kDa	No	0
NT5C1B-006 ENSP00000390811 ENST00000418427	H7BZQ4 [Direct mapping] Cytosolic 5'-nucleotidase 1B Show all	Predicted intracellular proteins Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0005737 [cytoplasm] GO:0008253 [5'-nucleotidase activity] GO:0009117 [nucleotide metabolic process] GO:0016311 [dephosphorylation] Show all	265 aa 29.6 kDa	No	0
NT5C1B-008 ENSP00000401656 ENST00000416783	C9JW75 [Direct mapping] Cytosolic 5'-nucleotidase 1B Show all	Predicted intracellular proteins Show all		206 aa 22.8 kDa	No	0