Expression of MYADML2 in cancer - Summary - The Human Protein Atlas

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MYADML2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MYADML2
Gene description	Myeloid-associated differentiation marker-like 2
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (colorectal cancer)
HPA (cell line):	Cell line enriched (SCLC-21H)
HPA (normal tissue):	Tissue enriched (skeletal muscle)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA041856 , HPA048476
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (colorectal cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA041856	HPA048476

GENE INFORMATION
Gene name	MYADML2 (HGNC Symbol)
Synonyms	LOC255275
Description	Myeloid-associated differentiation marker-like 2 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q25.3
Chromosome location (bp)	81939645 - 81947233
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000185105 (version 83.38)
Entrez gene	255275
UniProt	A6NDP7 (UniProt - Evidence at transcript level)
neXtProt	NX_A6NDP7
Antibodypedia	MYADML2 antibodies

PROTEIN BROWSER

MYADML2-001	MYADML2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MYADML2-001 ENSP00000386702 ENST00000409745	A6NDP7 [Direct mapping] Myeloid-associated differentiation marker-like protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Show all	GO:0005737 [cytoplasm] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	307 aa 33 kDa	No	8
MYADML2-201 ENSP00000327718 ENST00000330655	A6NDP7 [Direct mapping] Myeloid-associated differentiation marker-like protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Show all	GO:0005737 [cytoplasm] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	307 aa 33 kDa	No	8

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.