Tissue expression of INPP5J - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	INPP5J
Gene description	Inositol polyphosphate-5-phosphatase J
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	11
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (parathyroid gland, thyroid gland)
GTEx:	Tissue enhanced (thyroid gland)
FANTOM5:	Tissue enhanced (thyroid gland)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (parathyroid gland, thyroid gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (thyroid gland)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (thyroid gland)

GENE INFORMATION
Gene name	INPP5J (HGNC Symbol)
Synonyms	INPP5, PIB5PA
Description	Inositol polyphosphate-5-phosphatase J (HGNC Symbol)
Entrez gene summary
Chromosome	22
Cytoband	q12.2
Chromosome location (bp)	31122731 - 31134696
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000185133 (version 83.38)
Entrez gene	27124
UniProt	Q15735 (UniProt - Evidence at protein level)
neXtProt	NX_Q15735
Antibodypedia	INPP5J antibodies

PROTEIN BROWSER

INPP5J-001	INPP5J-002	INPP5J-003	INPP5J-004	INPP5J-006	INPP5J-007	INPP5J-008	INPP5J-010	INPP5J-011	INPP5J-201	INPP5J-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
INPP5J-001 ENSP00000383150 ENST00000400294	Q15735 [Direct mapping] Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Show all	Enzymes ENZYME proteins Hydrolases THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001726 [ruffle] GO:0004445 [inositol-polyphosphate 5-phosphatase activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006644 [phospholipid metabolic process] GO:0006661 [phosphatidylinositol biosynthetic process] GO:0017124 [SH3 domain binding] GO:0043647 [inositol phosphate metabolic process] GO:0044281 [small molecule metabolic process] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052658 [inositol-1,4,5-trisphosphate 5-phosphatase activity] GO:0052659 [inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity] Show all	639 aa 70.5 kDa	No	0
INPP5J-002 ENSP00000333262 ENST00000331075	Q15735 [Direct mapping] Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Show all	Enzymes ENZYME proteins Hydrolases THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001726 [ruffle] GO:0004445 [inositol-polyphosphate 5-phosphatase activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006644 [phospholipid metabolic process] GO:0006661 [phosphatidylinositol biosynthetic process] GO:0010977 [negative regulation of neuron projection development] GO:0017124 [SH3 domain binding] GO:0030426 [growth cone] GO:0031115 [negative regulation of microtubule polymerization] GO:0033137 [negative regulation of peptidyl-serine phosphorylation] GO:0034485 [phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity] GO:0043198 [dendritic shaft] GO:0043647 [inositol phosphate metabolic process] GO:0044281 [small molecule metabolic process] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052658 [inositol-1,4,5-trisphosphate 5-phosphatase activity] GO:0052659 [inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity] Show all	1006 aa 107.2 kDa	No	0
INPP5J-003 ENSP00000384596 ENST00000405300	Q15735 [Direct mapping] Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Show all	Enzymes ENZYME proteins Hydrolases THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001726 [ruffle] GO:0004445 [inositol-polyphosphate 5-phosphatase activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006644 [phospholipid metabolic process] GO:0006661 [phosphatidylinositol biosynthetic process] GO:0017124 [SH3 domain binding] GO:0043647 [inositol phosphate metabolic process] GO:0044281 [small molecule metabolic process] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052658 [inositol-1,4,5-trisphosphate 5-phosphatase activity] GO:0052659 [inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity] Show all	639 aa 70.5 kDa	No	0
INPP5J-004 ENSP00000384534 ENST00000404390	Q15735 [Direct mapping] Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Show all	Enzymes ENZYME proteins Hydrolases THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001726 [ruffle] GO:0004445 [inositol-polyphosphate 5-phosphatase activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006644 [phospholipid metabolic process] GO:0006661 [phosphatidylinositol biosynthetic process] GO:0017124 [SH3 domain binding] GO:0043647 [inositol phosphate metabolic process] GO:0044281 [small molecule metabolic process] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052658 [inositol-1,4,5-trisphosphate 5-phosphatase activity] GO:0052659 [inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity] Show all	638 aa 70.2 kDa	No	0
INPP5J-006 ENSP00000385264 ENST00000402238	B5MCL8 [Direct mapping] Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		345 aa 37.7 kDa	No	0
INPP5J-007 ENSP00000385343 ENST00000404453	B5MBZ3 [Direct mapping] Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		371 aa 40.8 kDa	No	0
INPP5J-008 ENSP00000384540 ENST00000401755	B5MBZ3 [Direct mapping] Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		371 aa 40.8 kDa	No	0
INPP5J-010 ENSP00000401124 ENST00000412985	C9K0M5 [Direct mapping] Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		144 aa 14.2 kDa	No	0
INPP5J-011 ENSP00000406570 ENST00000420017	C9J0H5 [Direct mapping] Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		102 aa 11.4 kDa	No	1
INPP5J-201 ENSP00000392924 ENST00000412277	B4DF95 [Direct mapping] Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; cDNA FLJ59315, highly similar to Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56) Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016787 [hydrolase activity] GO:0046856 [phosphatidylinositol dephosphorylation] Show all	939 aa 100.5 kDa	No	0
INPP5J-202 ENSP00000479645 ENST00000620191	A0A087WVS7 [Direct mapping] Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Show all	Phobius predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016787 [hydrolase activity] GO:0046856 [phosphatidylinositol dephosphorylation] Show all	571 aa 63.4 kDa	No	0