Expression of KLHL33 in cancer - Summary - The Human Protein Atlas

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KLHL33

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	KLHL33
Gene description	Kelch-like family member 33
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enriched (REH)
HPA (normal tissue):	Tissue enriched (skeletal muscle)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA056560
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA056560

GENE INFORMATION
Gene name	KLHL33
Synonyms
Description	Kelch-like family member 33 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	20428811 - 20435642
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000185271 (version 83.38)
Entrez gene	123103
UniProt	A6NCF5 (UniProt - Predicted)
neXtProt	NX_A6NCF5
Antibodypedia	KLHL33 antibodies

PROTEIN BROWSER

KLHL33-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KLHL33-001 ENSP00000341549 ENST00000344581	A6NCF5 [Direct mapping] Kelch-like protein 33 Show all	Predicted intracellular proteins Show all	GO:0003779 [actin binding] GO:0004842 [ubiquitin-protein transferase activity] GO:0005515 [protein binding] GO:0015629 [actin cytoskeleton] GO:0016567 [protein ubiquitination] GO:0031463 [Cul3-RING ubiquitin ligase complex] Show all	533 aa 57.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.