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This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Enzymes ENZYME proteins Transferases Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000979 [RNA polymerase II core promoter sequence-specific DNA binding] GO:0000993 [RNA polymerase II core binding] GO:0001162 [RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006325 [chromatin organization] GO:0006334 [nucleosome assembly] GO:0006469 [negative regulation of protein kinase activity] GO:0014904 [myotube cell development] GO:0018024 [histone-lysine N-methyltransferase activity] GO:0033138 [positive regulation of peptidyl-serine phosphorylation] GO:0034968 [histone lysine methylation] GO:0045184 [establishment of protein localization] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] GO:0071549 [cellular response to dexamethasone stimulus]
Enzymes ENZYME proteins Transferases Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)