Fields »
ABOUT
HELP
BLOG
FAAP100

GENERAL INFORMATION

Gene name

 FAAP100

Gene description

 Fanconi anemia core complex associated protein 100

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Pending external verification. Subcellular localization is contradicted by limited literature.

Reliability score

 Uncertain based on 2 antibodies.
HPA023954 , HPA026532
SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA023954
HPA026532

GENE INFORMATION

Gene name

 FAAP100 (HGNC Symbol)

Synonyms

 C17orf70, FLJ22175

Description

 Fanconi anemia core complex associated protein 100 (HGNC Symbol)

Entrez gene summary

 FAAP100 is a component of the Fanconi anemia (FA; MIM 277650) core complex and is required for core complex stability and FANCD2 (see MIM 227646) monoubiquitination (Ling et al., 2007 [PubMed 17396147]).[supplied by OMIM, Mar 2008]

Chromosome

 17

Cytoband

 q25.3

Chromosome location (bp)

 81539885 - 81553961

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000185504 (version 83.38)

Entrez gene

 80233

UniProt

 Q0VG06 (UniProt - Evidence at protein level)

neXtProt

 NX_Q0VG06

Antibodypedia

 FAAP100 antibodies

PROTEIN BROWSER
FAAP100-001
FAAP100-004
FAAP100-006
FAAP100-007
FAAP100-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FAAP100-001
ENSP00000333283
ENST00000327787
Q0VG06 [Direct mapping]
Fanconi anemia core complex-associated protein 100
Show all
   MEMSAT3 predicted membrane proteins
   SCAMPI predicted membrane proteins
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006281 [DNA repair]
GO:0036297 [interstrand cross-link repair]
GO:0043240 [Fanconi anaemia nuclear complex]
GO:0045111 [intermediate filament cytoskeleton]
Show all
 881 aa
93.4 kDa 		No 0
FAAP100-004
ENSP00000399674
ENST00000425898
E7EVV8 [Direct mapping]
Fanconi anemia-associated protein of 100 kDa
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006281 [DNA repair]
GO:0043240 [Fanconi anaemia nuclear complex]
GO:0045111 [intermediate filament cytoskeleton]
Show all
 530 aa
56.6 kDa 		No 0
FAAP100-006
ENSP00000443415
ENST00000536161
F5H5G6 [Direct mapping]
Fanconi anemia-associated protein of 100 kDa
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 172 aa
18 kDa 		No 0
FAAP100-007
ENSP00000444241
ENST00000544302
F5GZS4 [Direct mapping]
Fanconi anemia-associated protein of 100 kDa
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 249 aa
25.8 kDa 		No 0
FAAP100-008
ENSP00000438149
ENST00000541246
F5H095 [Direct mapping]
Fanconi anemia-associated protein of 100 kDa
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 301 aa
31.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.