Expression of FAM131C in cancer - Summary - The Human Protein Atlas

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FAM131C

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM131C
Gene description	Family with sequence similarity 131, member C
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (A549, HEK93, PC-3)
HPA (normal tissue):	Tissue enhanced (adrenal gland, cerebral cortex, kidney)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA031046
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA031046

GENE INFORMATION
Gene name	FAM131C (HGNC Symbol)
Synonyms	C1orf117, FLJ36766
Description	Family with sequence similarity 131, member C (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p36.13
Chromosome location (bp)	16057769 - 16073632
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000185519 (version 83.38)
Entrez gene	348487
UniProt	Q96AQ9 (UniProt - Evidence at protein level)
neXtProt	NX_Q96AQ9
Antibodypedia	FAM131C antibodies

PROTEIN BROWSER

FAM131C-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM131C-001 ENSP00000364814 ENST00000375662	Q96AQ9 [Direct mapping] Protein FAM131C Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	280 aa 30.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.