Expression of DBX2 in cancer - Summary - The Human Protein Atlas

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DBX2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	DBX2
Gene description	Developing brain homeobox 2
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (glioma)
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (cerebral cortex, testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA066053
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (glioma)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA066053

GENE INFORMATION
Gene name	DBX2 (HGNC Symbol)
Synonyms	FLJ16139
Description	Developing brain homeobox 2 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q12
Chromosome location (bp)	45014672 - 45051099
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000185610 (version 83.38)
Entrez gene	440097
UniProt	Q6ZNG2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6ZNG2
Antibodypedia	DBX2 antibodies

PROTEIN BROWSER

DBX2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DBX2-001 ENSP00000331470 ENST00000332700	Q6ZNG2 [Direct mapping] Homeobox protein DBX2 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0043565 [sequence-specific DNA binding] Show all	339 aa 36.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.