Cell atlas - PCGF3 - The Human Protein Atlas

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PCGF3

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	PCGF3
Gene description	Polycomb group ring finger 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA061879
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA061879	Hep G2	Nucleoplasm
	HPA061879	PC-3	Nucleoplasm
	HPA061879	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	PCGF3 (HGNC Symbol)
Synonyms	DONG1, FLJ36550, MGC40413, RNF3, RNF3A
Description	Polycomb group ring finger 3 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene contains a C3HC4 type RING finger, which is a motif known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. [provided by RefSeq, Jul 2008]
Chromosome	4
Cytoband	p16.3
Chromosome location (bp)	705748 - 770640
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000185619 (version 83.38)
Entrez gene	10336
UniProt	Q3KNV8 (UniProt - Evidence at protein level)
neXtProt	NX_Q3KNV8
Antibodypedia	PCGF3 antibodies

PROTEIN BROWSER

PCGF3-001	PCGF3-004	PCGF3-005	PCGF3-007	PCGF3-009	PCGF3-012	PCGF3-201	PCGF3-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PCGF3-001 ENSP00000354724 ENST00000362003	Q3KNV8 [Direct mapping] Polycomb group RING finger protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0031519 [PcG protein complex] GO:0046872 [metal ion binding] Show all	242 aa 28.1 kDa	No	0
PCGF3-004 ENSP00000420489 ENST00000470161	Q3KNV8 [Direct mapping] Polycomb group RING finger protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0031519 [PcG protein complex] GO:0046872 [metal ion binding] Show all	242 aa 28.1 kDa	No	0
PCGF3-005 ENSP00000398493 ENST00000433814	C9J3G7 [Direct mapping] Polycomb group RING finger protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	109 aa 12.8 kDa	No	0
PCGF3-007 ENSP00000416279 ENST00000419774	C9JGV3 [Direct mapping] Polycomb group RING finger protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0046872 [metal ion binding] Show all	40 aa 4.6 kDa	No	0
PCGF3-009 ENSP00000383015 ENST00000400151	B5MEC4 [Direct mapping] Polycomb group RING finger protein 3 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		173 aa 19.1 kDa	No	0
PCGF3-012 ENSP00000401431 ENST00000427463	C9JYD0 [Direct mapping] Polycomb group RING finger protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	62 aa 7.2 kDa	No	0
PCGF3-201 ENSP00000423393 ENST00000505655	Q3KNV8 [Direct mapping] Polycomb group RING finger protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0031519 [PcG protein complex] GO:0046872 [metal ion binding] Show all	242 aa 28.1 kDa	No	0
PCGF3-202 ENSP00000479441 ENST00000620529	A0A087WVH5 [Direct mapping] Polycomb group RING finger protein 3 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	132 aa 14.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.