Expression of CXorf38 in cancer - Summary - The Human Protein Atlas

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CXorf38

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CXorf38
Gene description	Chromosome X open reading frame 38
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear and granular expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA050120
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PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable) and pancreatic cancer (unfavourable).
Urothelial cancer p<0.001 Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA050120

GENE INFORMATION
Gene name	CXorf38 (HGNC Symbol)
Synonyms	MGC39350
Description	Chromosome X open reading frame 38 (HGNC Symbol)
Entrez gene summary
Chromosome	X
Cytoband	p11.4
Chromosome location (bp)	40626921 - 40647554
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000185753 (version 83.38)
Entrez gene	159013
UniProt	Q8TB03 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TB03
Antibodypedia	CXorf38 antibodies

PROTEIN BROWSER

CXorf38-001	CXorf38-002	CXorf38-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CXorf38-001 ENSP00000367683 ENST00000378426	Q8TB03 [Direct mapping] Uncharacterized protein CXorf38 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		200 aa 23.3 kDa	No	0
CXorf38-002 ENSP00000367677 ENST00000378421	Q8TB03 [Direct mapping] Uncharacterized protein CXorf38 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		200 aa 23.3 kDa	No	0
CXorf38-003 ENSP00000330488 ENST00000327877	Q8TB03 [Direct mapping] Uncharacterized protein CXorf38 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		319 aa 36.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.