Expression of MORF4L1 in cancer - Summary - The Human Protein Atlas

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MORF4L1

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MORF4L1
Gene description	Mortality factor 4 like 1
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	13
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Mainly nuclear expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA042360
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042360

GENE INFORMATION
Gene name	MORF4L1 (HGNC Symbol)
Synonyms	Eaf3, HsT17725, MEAF3, MORFRG15, MRG15
Description	Mortality factor 4 like 1 (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q25.1
Chromosome location (bp)	78810487 - 78898133
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000185787 (version 83.38)
Entrez gene	10933
UniProt	Q9UBU8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UBU8
Antibodypedia	MORF4L1 antibodies

PROTEIN BROWSER

MORF4L1-001	MORF4L1-002	MORF4L1-003	MORF4L1-007	MORF4L1-009	MORF4L1-010	MORF4L1-011	MORF4L1-012	MORF4L1-014	MORF4L1-017	MORF4L1-021	MORF4L1-022	MORF4L1-023

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MORF4L1-001 ENSP00000331310 ENST00000331268	Q9UBU8 [Direct mapping] Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000724 [double-strand break repair via homologous recombination] GO:0003682 [chromatin binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006325 [chromatin organization] GO:0006338 [chromatin remodeling] GO:0006342 [chromatin silencing] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008283 [cell proliferation] GO:0016568 [chromatin modification] GO:0016575 [histone deacetylation] GO:0016580 [Sin3 complex] GO:0035267 [NuA4 histone acetyltransferase complex] GO:0040008 [regulation of growth] GO:0043967 [histone H4 acetylation] GO:0043968 [histone H2A acetylation] GO:0047485 [protein N-terminus binding] Show all	362 aa 41.5 kDa	No	0
MORF4L1-002 ENSP00000408880 ENST00000426013	Q9UBU8 [Direct mapping] Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000724 [double-strand break repair via homologous recombination] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006325 [chromatin organization] GO:0006338 [chromatin remodeling] GO:0006342 [chromatin silencing] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] GO:0016575 [histone deacetylation] GO:0016580 [Sin3 complex] GO:0035267 [NuA4 histone acetyltransferase complex] GO:0040008 [regulation of growth] GO:0043967 [histone H4 acetylation] GO:0043968 [histone H2A acetylation] GO:0047485 [protein N-terminus binding] Show all	323 aa 37.2 kDa	No	0
MORF4L1-003 ENSP00000452717 ENST00000559345	Q9UBU8 [Direct mapping] Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000724 [double-strand break repair via homologous recombination] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0006325 [chromatin organization] GO:0006338 [chromatin remodeling] GO:0006342 [chromatin silencing] GO:0006351 [transcription, DNA-templated] GO:0016575 [histone deacetylation] GO:0016580 [Sin3 complex] GO:0035267 [NuA4 histone acetyltransferase complex] GO:0040008 [regulation of growth] GO:0043967 [histone H4 acetylation] GO:0043968 [histone H2A acetylation] GO:0047485 [protein N-terminus binding] Show all	235 aa 26.7 kDa	No	0
MORF4L1-007 ENSP00000368850 ENST00000379535	B3KTM8 [Direct mapping] Mortality factor 4-like protein 1; cDNA FLJ38504 fis, clone HCHON2000156, highly similar to Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] Show all	348 aa 40 kDa	No	0
MORF4L1-009 ENSP00000453625 ENST00000560422	H0YMJ0 [Direct mapping] Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] Show all	245 aa 28.2 kDa	No	0
MORF4L1-010 ENSP00000453351 ENST00000559690	H0YLV1 [Direct mapping] Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] Show all	113 aa 12.9 kDa	No	0
MORF4L1-011 ENSP00000453432 ENST00000559158	H0YM21 [Direct mapping] Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] Show all	156 aa 17.9 kDa	No	0
MORF4L1-012 ENSP00000454191 ENST00000559930	H0YNX3 [Direct mapping] Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] Show all	74 aa 8.1 kDa	No	0
MORF4L1-014 ENSP00000454030 ENST00000559244	H0YNI8 [Direct mapping] Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] Show all	58 aa 6.2 kDa	No	0
MORF4L1-017 ENSP00000453972 ENST00000559751	H0YNE0 [Direct mapping] Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] Show all	213 aa 24.4 kDa	No	0
MORF4L1-021 ENSP00000453231 ENST00000558746	H0YLJ3 [Direct mapping] Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] Show all	269 aa 31.3 kDa	No	0
MORF4L1-022 ENSP00000453738 ENST00000558830	H0YMT8 [Direct mapping] Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] Show all	119 aa 13.5 kDa	No	0
MORF4L1-023 ENSP00000452808 ENST00000558502	Q9UBU8 [Direct mapping] Mortality factor 4-like protein 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000724 [double-strand break repair via homologous recombination] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0006325 [chromatin organization] GO:0006338 [chromatin remodeling] GO:0006342 [chromatin silencing] GO:0006351 [transcription, DNA-templated] GO:0016575 [histone deacetylation] GO:0016580 [Sin3 complex] GO:0035267 [NuA4 histone acetyltransferase complex] GO:0040008 [regulation of growth] GO:0043967 [histone H4 acetylation] GO:0043968 [histone H2A acetylation] GO:0047485 [protein N-terminus binding] Show all	235 aa 26.7 kDa	No	0

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