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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

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Searches

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Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

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Score

Score

Score

Antibodies

Column

 
 
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TAS2R60
  • TISSUE

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PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

TAS2R60

Gene description

Taste receptor, type 2, member 60

Protein class

G-protein coupled receptors
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Not detected

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

RNA-based expert annotation gave inconclusive results. No RNA expression data detected and pending external verification.

Reliability score

Uncertain based on 1 antibody.
HPA030416
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PROGNOSTIC SUMMARY

Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA030416

Cancer

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Cancer

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

A few cases of hepatocellular carcinomas, seminomas, pancreatic and stomach cancers displayed moderate to strong cytoplasmic immunoreactivity. Remaining malignant cells were either negative or weakly stained.

GENE INFORMATION

Gene name

TAS2R60 (HGNC Symbol)

Synonyms

T2R60

Description

Taste receptor, type 2, member 60 (HGNC Symbol)

Entrez gene summary

Chromosome

7

Cytoband

q35

Chromosome location (bp)

143443453 - 143444409

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000185899 (version 83.38)

Entrez gene

338398

UniProt

P59551 (UniProt - Evidence at transcript level)

neXtProt

NX_P59551

Antibodypedia

TAS2R60 antibodies

PROTEIN BROWSER

TAS2R60-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TAS2R60-001
ENSP00000327724
ENST00000332690
P59551 [Direct mapping]
Taste receptor type 2 member 60
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G-protein coupled receptors
   GPCRs excl olfactory receptors
   Family T2R receptors (taste receptor GPCRs)
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Show all
GO:0004930 [G-protein coupled receptor activity]
GO:0005886 [plasma membrane]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0016021 [integral component of membrane]
GO:0050909 [sensory perception of taste]
GO:0050913 [sensory perception of bitter taste]
Show all
318 aa
36.3 kDa
No 8

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