Tissue expression of CD300LF - Summary - The Human Protein Atlas

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CD300LF

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TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CD300LF
Gene description	CD300 molecule-like family member f
Protein class	CD markers Predicted intracellular proteins Predicted membrane proteins Predicted secreted proteins
Predicted localization	Intracellular,Membrane,Secreted
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (lung, spleen)
GTEx:	Group enriched (lung, spleen)
FANTOM5:	Tissue enhanced (lung, spleen)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in immune cells and sinusoids in several different tissues, most abundant in spleen.

DATA RELIABILITY
Data reliability description	Presumed off target binding observed and disregarded. Antibody staining in cells/structures not annotated, view images.
Reliability score	Supported based on 1 antibody. HPA013712
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (lung, spleen)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (lung, spleen)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (lung, spleen)

GENE INFORMATION
Gene name	CD300LF (HGNC Symbol)
Synonyms	CD300f, CLM1, IGSF13, IREM1, NKIR
Description	CD300 molecule-like family member f (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. The encoded protein is an inhibitory receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Chromosome	17
Cytoband	q25.1
Chromosome location (bp)	74694311 - 74712978
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000186074 (version 83.38)
Entrez gene	146722
UniProt	Q8TDQ1 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TDQ1
Antibodypedia	CD300LF antibodies

PROTEIN BROWSER

CD300LF-001	CD300LF-002	CD300LF-003	CD300LF-005	CD300LF-006	CD300LF-007	CD300LF-201	CD300LF-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CD300LF-001 ENSP00000327075 ENST00000326165	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	290 aa 32.3 kDa	Yes	1
CD300LF-002 ENSP00000463743 ENST00000469092	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	194 aa 21.4 kDa	No	0
CD300LF-003 ENSP00000464257 ENST00000464910	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	293 aa 32.6 kDa	No	1
CD300LF-005 ENSP00000464610 ENST00000581500	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	239 aa 26.5 kDa	No	1
CD300LF-006 ENSP00000462309 ENST00000583937	J3KS52 [Direct mapping] CMRF35-like molecule 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	305 aa 33.8 kDa	Yes	1
CD300LF-007 ENSP00000301573 ENST00000301573	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	244 aa 26.7 kDa	Yes	0
CD300LF-201 ENSP00000343751 ENST00000343125	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	194 aa 21.4 kDa	No	0
CD300LF-202 ENSP00000355294 ENST00000361254	Q8TDQ1 [Direct mapping] CMRF35-like molecule 1 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	239 aa 26.5 kDa	No	1

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.