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BCL9L

GENERAL INFORMATION

Gene name

 BCL9L

Gene description

 B-cell CLL/lymphoma 9-like

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Nuclear and cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA049370
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA049370

GENE INFORMATION

Gene name

 BCL9L (HGNC Symbol)

Synonyms

 DLNB11

Description

 B-cell CLL/lymphoma 9-like (HGNC Symbol)

Entrez gene summary

Chromosome

 11

Cytoband

 q23.3

Chromosome location (bp)

 118893875 - 118925608

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000186174 (version 83.38)

Entrez gene

 283149

UniProt

 Q86UU0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q86UU0

Antibodypedia

 BCL9L antibodies

PROTEIN BROWSER
BCL9L-001
BCL9L-002
BCL9L-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
BCL9L-001
ENSP00000335320
ENST00000334801
Q86UU0 [Direct mapping]
B-cell CLL/lymphoma 9-like protein
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003713 [transcription coactivator activity]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0006351 [transcription, DNA-templated]
GO:0008013 [beta-catenin binding]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0022604 [regulation of cell morphogenesis]
GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway]
GO:0035019 [somatic stem cell population maintenance]
GO:0035914 [skeletal muscle cell differentiation]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0060070 [canonical Wnt signaling pathway]
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 1499 aa
157.1 kDa 		No 0
BCL9L-002
ENSP00000482938
ENST00000526143
A0A087WZX0 [Direct mapping]
B-cell CLL/lymphoma 9-like protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 1462 aa
153.1 kDa 		No 0
BCL9L-006
ENSP00000432804
ENST00000532899
E9PNR0 [Direct mapping]
B-cell CLL/lymphoma 9-like protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 88 aa
9.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.