Cell atlas - KRT10 - The Human Protein Atlas

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KRT10

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TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	KRT10
Gene description	Keratin 10, type I
Protein class	Disease related genes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (hTCEpi)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (hTCEpi) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	KRT10 (HGNC Symbol)
Synonyms	CK10, K10, KPP
Description	Keratin 10, type I (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008]
Chromosome	17
Cytoband	q21.2
Chromosome location (bp)	40818117 - 40822595
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000186395 (version 83.38)
Entrez gene	3858
UniProt	P13645 (UniProt - Evidence at protein level)
neXtProt	NX_P13645
Antibodypedia	KRT10 antibodies

PROTEIN BROWSER

KRT10-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KRT10-002 ENSP00000269576 ENST00000269576	P13645 [Direct mapping] Keratin, type I cytoskeletal 10 Show all	Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005198 [structural molecule activity] GO:0005615 [extracellular space] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005882 [intermediate filament] GO:0016020 [membrane] GO:0030216 [keratinocyte differentiation] GO:0030280 [structural constituent of epidermis] GO:0030855 [epithelial cell differentiation] GO:0045095 [keratin filament] GO:0070062 [extracellular exosome] GO:0071277 [cellular response to calcium ion] Show all	584 aa 58.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.