Expression of CCDC30 in cancer - Summary - The Human Protein Atlas

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CCDC30

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CCDC30
Gene description	Coiled-coil domain containing 30
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enriched (HMC-1)
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Granular cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA036344 , HPA036345
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036344	HPA036345

GENE INFORMATION
Gene name	CCDC30 (HGNC Symbol)
Synonyms	FLJ20972, LOC728621, PFD6L
Description	Coiled-coil domain containing 30 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p34.2
Chromosome location (bp)	42463330 - 42654664
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000186409 (version 83.38)
Entrez gene	728621
UniProt	Q5VVM6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5VVM6
Antibodypedia	CCDC30 antibodies

PROTEIN BROWSER

CCDC30-001	CCDC30-013	CCDC30-201	CCDC30-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC30-001 ENSP00000340378 ENST00000340612	Q5VVM6 [Direct mapping] Coiled-coil domain-containing protein 30 Show all	Predicted intracellular proteins Show all	GO:0070062 [extracellular exosome] Show all	783 aa 91.3 kDa	No	0
CCDC30-013 ENSP00000426711 ENST00000507855	Q5VVM6 [Direct mapping] Coiled-coil domain-containing protein 30 Show all	Predicted intracellular proteins Show all	GO:0070062 [extracellular exosome] Show all	572 aa 67.2 kDa	No	0
CCDC30-201 ENSP00000339280 ENST00000342022	Q5VVM6 [Direct mapping] Coiled-coil domain-containing protein 30 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0070062 [extracellular exosome] Show all	783 aa 91.3 kDa	No	0
CCDC30-202 ENSP00000397035 ENST00000428554	Q5VVM6 [Direct mapping] Coiled-coil domain-containing protein 30 Show all	Predicted intracellular proteins Show all	GO:0070062 [extracellular exosome] Show all	783 aa 91.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.