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ARHGAP30

GENERAL INFORMATION

Gene name

 ARHGAP30

Gene description

 Rho GTPase activating protein 30

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (lymph node, spleen)
GTEx:Tissue enhanced (spleen)
FANTOM5:Tissue enhanced (appendix, tonsil)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in selected tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA036300
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Appendix

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical
Cerebral cortexHippocampusCaudateCerebellumThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleNasopharynxBronchusLungLiverGallbladderPancreasOral mucosaSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSoft tissueSkinNotdetectedLowMediumHighSCORE

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (lymph node, spleen)
Cerebral cortexThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSkin020406080100TPM
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (spleen)
HypothalamusPituitary glandCerebral cortexHippocampusCaudateCerebellumThyroid glandAdrenal glandSpleenHeart muscleSkeletal muscleLungLiverPancreasSalivary glandEsophagusStomachSmall intestineColonKidneyUrinary bladderTestisProstateBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryAdipose tissueSkin010203040506070RPKM
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (appendix, tonsil)
Pituitary glandBrainHippocampusCaudateCerebellumThyroid glandAppendixLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusSmall intestineColonKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumOvaryPlacentaAdipose tissueRetina010203040506070Tags Per Million

GENE INFORMATION

Gene name

 ARHGAP30 (HGNC Symbol)

Synonyms

 FLJ00267

Description

 Rho GTPase activating protein 30 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 q23.3

Chromosome location (bp)

 161046946 - 161069970

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000186517 (version 83.38)

Entrez gene

 257106

UniProt

 Q7Z6I6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q7Z6I6

Antibodypedia

 ARHGAP30 antibodies

PROTEIN BROWSER
ARHGAP30-001
ARHGAP30-002
ARHGAP30-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ARHGAP30-001
ENSP00000356995
ENST00000368016
A0A0A0MRJ9 [Direct mapping]
Rho GTPase-activating protein 30
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0007165 [signal transduction]
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 890 aa
95.5 kDa 		No 0
ARHGAP30-002
ENSP00000356994
ENST00000368015
A0A0A0MRJ8 [Direct mapping]
Rho GTPase-activating protein 30
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 924 aa
98.1 kDa 		No 0
ARHGAP30-007
ENSP00000356992
ENST00000368013
Q7Z6I6 [Direct mapping]
Rho GTPase-activating protein 30
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005096 [GTPase activator activity]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0016023 [cytoplasmic membrane-bounded vesicle]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043547 [positive regulation of GTPase activity]
GO:0051056 [regulation of small GTPase mediated signal transduction]
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 1101 aa
118.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.