Expression of SPATC1 in cancer - Summary - The Human Protein Atlas

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SPATC1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SPATC1
Gene description	Spermatogenesis and centriole associated 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enriched (U-937)
HPA (normal tissue):	Group enriched (bone marrow, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA039590 , HPA040220
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA039590	HPA040220

GENE INFORMATION
Gene name	SPATC1 (HGNC Symbol)
Synonyms	MGC61633, SPATA15, SPERIOLIN
Description	Spermatogenesis and centriole associated 1 (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	q24.3
Chromosome location (bp)	144012414 - 144047085
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000186583 (version 83.38)
Entrez gene	375686
UniProt	Q76KD6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q76KD6
Antibodypedia	SPATC1 antibodies

PROTEIN BROWSER

SPATC1-001	SPATC1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SPATC1-001 ENSP00000366690 ENST00000377470	Q76KD6 [Direct mapping] Speriolin Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005813 [centrosome] Show all	591 aa 62.4 kDa	No	0
SPATC1-002 ENSP00000387613 ENST00000447830	Q76KD6 [Direct mapping] Speriolin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005813 [centrosome] Show all	441 aa 45.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.