Cell atlas - FSD2 - The Human Protein Atlas

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FSD2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	FSD2
Gene description	Fibronectin type III and SPRY domain containing 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA046263
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA046263	HaCaT	Cytosol
	HPA046263	U-2 OS	Cytosol

GENE INFORMATION
Gene name	FSD2 (HGNC Symbol)
Synonyms	RP11-127F21, SPRYD1
Description	Fibronectin type III and SPRY domain containing 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that belongs to the FN3/SPRY family of proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Chromosome	15
Cytoband	q25.2
Chromosome location (bp)	82755362 - 82806070
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000186628 (version 83.38)
Entrez gene	123722
UniProt	A1L4K1 (UniProt - Evidence at protein level)
neXtProt	NX_A1L4K1
Antibodypedia	FSD2 antibodies

PROTEIN BROWSER

FSD2-001	FSD2-002	FSD2-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FSD2-001 ENSP00000444078 ENST00000541889	A1L4K1 [Direct mapping] Fibronectin type III and SPRY domain-containing protein 2 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	704 aa 80.3 kDa	No	0
FSD2-002 ENSP00000335651 ENST00000334574	A1L4K1 [Direct mapping] Fibronectin type III and SPRY domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	749 aa 85.4 kDa	No	0
FSD2-003 ENSP00000453127 ENST00000561368	H0YLA8 [Direct mapping] Fibronectin type III and SPRY domain-containing protein 2 Show all	Predicted intracellular proteins Show all		101 aa 11.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.