Expression of HYPM in cancer - Summary - The Human Protein Atlas

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HYPM

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	HYPM
Gene description	Huntingtin interacting protein M
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA003356
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA003356

GENE INFORMATION
Gene name	HYPM (HGNC Symbol)
Synonyms	CXorf27, HIP17
Description	Huntingtin interacting protein M (HGNC Symbol)
Entrez gene summary	This gene encodes a protein shown to interact with huntingtin, which contains an expanded polyglutamine tract in individuals with Huntington's disease (PMID: 9700202). [provided by RefSeq, Aug 2011]
Chromosome	X
Cytoband	p11.4
Chromosome location (bp)	37990817 - 37991317
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000187516 (version 83.38)
Entrez gene	25763
UniProt	O75409 (UniProt - Evidence at protein level)
neXtProt	NX_O75409
Antibodypedia	HYPM antibodies

PROTEIN BROWSER

HYPM-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HYPM-001 ENSP00000339511 ENST00000341016	O75409 [Direct mapping] Huntingtin-interacting protein M Show all	Predicted intracellular proteins Show all	GO:0000790 [nuclear chromatin] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0006325 [chromatin organization] GO:0006342 [chromatin silencing] GO:0046982 [protein heterodimerization activity] Show all	117 aa 13.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.