Expression of ATP13A5 in cancer - Summary - The Human Protein Atlas

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ATP13A5

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ATP13A5
Gene description	ATPase type 13A5
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (head and neck cancer)
HPA (cell line):	Cell line enhanced (SK-BR-3)
HPA (normal tissue):	Tissue enhanced (breast)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA031771 , HPA031774
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (head and neck cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA031771	HPA031774

GENE INFORMATION
Gene name	ATP13A5 (HGNC Symbol)
Synonyms	FLJ16025
Description	ATPase type 13A5 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q29
Chromosome location (bp)	193274790 - 193378843
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000187527 (version 83.38)
Entrez gene	344905
UniProt	Q4VNC0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q4VNC0
Antibodypedia	ATP13A5 antibodies

PROTEIN BROWSER

ATP13A5-001	ATP13A5-005	ATP13A5-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATP13A5-001 ENSP00000341942 ENST00000342358	Q4VNC0 [Direct mapping] Probable cation-transporting ATPase 13A5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0000166 [nucleotide binding] GO:0005524 [ATP binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006812 [cation transport] GO:0006874 [cellular calcium ion homeostasis] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0016887 [ATPase activity] GO:0019829 [cation-transporting ATPase activity] GO:0034220 [ion transmembrane transport] GO:0043231 [intracellular membrane-bounded organelle] GO:0046872 [metal ion binding] GO:0055085 [transmembrane transport] GO:0098655 [cation transmembrane transport] Show all	1218 aa 137.3 kDa	No	>9
ATP13A5-005 ENSP00000389416 ENST00000446087	C9JPQ4 [Direct mapping] Probable cation-transporting ATPase 13A5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0006812 [cation transport] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0016887 [ATPase activity] Show all	158 aa 18.4 kDa	No	1
ATP13A5-201 ENSP00000483801 ENST00000620313	A0A087X108 [Direct mapping] Probable cation-transporting ATPase 13A5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	114 aa 13.5 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.