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CYP26C1

GENERAL INFORMATION

Gene name

 CYP26C1

Gene description

 Cytochrome P450, family 26, subfamily C, polypeptide 1

Protein class

 Disease related genes
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Not detected

Protein evidence

 Evidence at transcript level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 CYP26C1

Synonyms

Description

 Cytochrome P450, family 26, subfamily C, polypeptide 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues. This gene is adjacent to a related gene on chromosome 10q23.33. [provided by RefSeq, Jul 2008]

Chromosome

 10

Cytoband

 q23.33

Chromosome location (bp)

 93060808 - 93069536

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000187553 (version 83.38)

Entrez gene

 340665

UniProt

 Q6V0L0 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q6V0L0

Antibodypedia

 CYP26C1 antibodies

PROTEIN BROWSER
CYP26C1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CYP26C1-001
ENSP00000285949
ENST00000285949
Q6V0L0 [Direct mapping]
Cytochrome P450 26C1
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Disease related genes
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GO:0001972 [retinoic acid binding]
GO:0005506 [iron ion binding]
GO:0005789 [endoplasmic reticulum membrane]
GO:0006766 [vitamin metabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0007417 [central nervous system development]
GO:0008401 [retinoic acid 4-hydroxylase activity]
GO:0009952 [anterior/posterior pattern specification]
GO:0014032 [neural crest cell development]
GO:0016021 [integral component of membrane]
GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen]
GO:0020037 [heme binding]
GO:0034653 [retinoic acid catabolic process]
GO:0044281 [small molecule metabolic process]
GO:0048284 [organelle fusion]
GO:0048387 [negative regulation of retinoic acid receptor signaling pathway]
GO:0055114 [oxidation-reduction process]
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 522 aa
57.1 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.