Expression of TMEM8C in cancer - Summary - The Human Protein Atlas

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TMEM8C

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TMEM8C
Gene description	Transmembrane protein 8C
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enriched (RH-30)
HPA (normal tissue):	Not detected

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. No RNA expression data detected and pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA051846 , HPA055785
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA051846	HPA055785

GENE INFORMATION
Gene name	TMEM8C (HGNC Symbol)
Synonyms	TMEM226
Description	Transmembrane protein 8C (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	q34.2
Chromosome location (bp)	133514586 - 133528612
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000187616 (version 83.38)
Entrez gene	389827
UniProt	A6NI61 (UniProt - Inferred from homology)
neXtProt	NX_A6NI61
Antibodypedia	TMEM8C antibodies

PROTEIN BROWSER

TMEM8C-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM8C-002 ENSP00000419712 ENST00000339996	A6NI61 [Direct mapping] Protein myomaker Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005886 [plasma membrane] GO:0007517 [muscle organ development] GO:0007520 [myoblast fusion] GO:0016021 [integral component of membrane] GO:0045026 [plasma membrane fusion] Show all	221 aa 24.7 kDa	Yes	6

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.