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SSX7

GENERAL INFORMATION

Gene name

 SSX7

Gene description

 Synovial sarcoma, X breakpoint 7

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Cell line enhanced (HMC-1, RT4)
HPA (normal tissue):Not detected

Protein evidence

 Evidence at transcript level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene.

Reliability score

 Uncertain based on 1 antibody.
HPA045683
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA045683

GENE INFORMATION

Gene name

 SSX7

Synonyms

Description

 Synovial sarcoma, X breakpoint 7 (HGNC Symbol)

Entrez gene summary

 The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. [provided by RefSeq, Jul 2008]

Chromosome

 X

Cytoband

 p11.22

Chromosome location (bp)

 52644090 - 52654900

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000187754 (version 83.38)

Entrez gene

 280658

UniProt

 Q7RTT5 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q7RTT5

Antibodypedia

 SSX7 antibodies

PROTEIN BROWSER
SSX7-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SSX7-001
ENSP00000298181
ENST00000298181
Q7RTT5 [Direct mapping]
Protein SSX7
A0A024R019 [Target identity:100%; Query identity:100%]
Synovial sarcoma, X breakpoint 7, isoform CRA_a
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Predicted intracellular proteins
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GO:0003676 [nucleic acid binding]
GO:0003714 [transcription corepressor activity]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:1903507 [negative regulation of nucleic acid-templated transcription]
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 188 aa
21.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.