Expression of C17orf99 in cancer - Summary - The Human Protein Atlas

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C17orf99

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C17orf99
Gene description	Chromosome 17 open reading frame 99
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Group enriched (HaCaT, HMC-1, K-562)
HPA (normal tissue):	Tissue enriched (bone marrow)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Uncertain based on 1 antibody. HPA029655
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA029655

GENE INFORMATION
Gene name	C17orf99 (HGNC Symbol)
Synonyms	GLPG464, UNQ464
Description	Chromosome 17 open reading frame 99 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q25.3
Chromosome location (bp)	78146353 - 78166177
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000187997 (version 83.38)
Entrez gene	100141515
UniProt	Q6UX52 (UniProt - Evidence at protein level)
neXtProt	NX_Q6UX52
Antibodypedia	C17orf99 antibodies

PROTEIN BROWSER

C17orf99-001	C17orf99-003	C17orf99-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C17orf99-001 ENSP00000343493 ENST00000340363	Q6UX52 [Direct mapping] Uncharacterized protein C17orf99 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] Show all	265 aa 29.1 kDa	Yes	0
C17orf99-003 ENSP00000466133 ENST00000591995	K7ELL6 [Direct mapping] Uncharacterized protein C17orf99 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		189 aa 20.8 kDa	No	0
C17orf99-005 ENSP00000487393 ENST00000586029	A0A0D9SGD8 [Direct mapping] Uncharacterized protein C17orf99 Show all	Predicted intracellular proteins Show all		151 aa 16.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.