Expression of FAM25A in cancer - Summary - The Human Protein Atlas

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FAM25A

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM25A
Gene description	Family with sequence similarity 25, member A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (head and neck cancer)
HPA (cell line):	Group enriched (A-431, SK-BR-3)
HPA (normal tissue):	Tissue enhanced (esophagus, skin)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Expression in esophagus, skin and vagina.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.
Reliability score	Uncertain based on 1 antibody. HPA044808
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (head and neck cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044808

GENE INFORMATION
Gene name	FAM25A (HGNC Symbol)
Synonyms	bA96C23.5
Description	Family with sequence similarity 25, member A (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q23.2
Chromosome location (bp)	87020306 - 87024730
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000188100 (version 83.38)
Entrez gene	643161
UniProt	B3EWG3 (UniProt - Inferred from homology,UniProt - Uncertain), B3EWG4 (UniProt - Inferred from homology,UniProt - Uncertain)
neXtProt	NX_B3EWG3, NX_B3EWG4
Antibodypedia	FAM25A antibodies

PROTEIN BROWSER

FAM25A-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM25A-001 ENSP00000342790 ENST00000343959	B3EWG3 [Direct mapping] Protein FAM25A B3EWG4 [Target identity:100%; Query identity:100%] Putative protein FAM25BP Show all	Predicted intracellular proteins Show all		89 aa 9.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.